Manchester United, who lie eighth in the premier league are looking to bounce back from their defeat at Westham United and secure a third victory of the season.
Arsenal who are four places and three points ahead of their hosts, are aiming for a second consecutive premier league win after coming back with ten men to beat Aston Villa on Sunday during the match week six.
Paul Pogba (ankle) and Marcus Rashford (groin) are doubts for Manchester United who are without injured players Anthony Martial, Phil Jones, Eric Bailly, Diogo Dalot, Angel Gomes and Tim Fosu-Mensah.
Luke Show is fast recovering from a thigh problem and has a chance of featuring. Arsenal could play Hector Bellerin and Kieran Tierney for the first time in the premier league after the full back returned from long-term injuries in the Carabao Cup vs Nottingham Forest. Dinos Mavropanos is available having built up his fitness but Alexandre Lacazette’s ankle injury has been joined on the sidelines by Emile Smith Rowe’s head injury.